Isla Caja De Muertos, an uninhabited natural reserve off Puerto Rico's southern coast, offers a pristine escape for a full-day excursion, typically lasting 6-7 hours including travel. Access is primarily via daily ferry services from La Guancha in Ponce, costing approximately $30-$50 per person for a round trip; advance booking is highly recommended, particularly during peak seasons or weekends. While guided tours handle transportation, visitors are free to explore the island independently, hiking to its historic lighthouse for panoramic views, snorkeling in its clear waters (especially at Playa Pelicano), or relaxing on its beautiful beaches. The island is moderately accessible, with sandy paths and some boardwalks; however, the lighthouse trail involves an uphill walk, making it less suitable for those with significant mobility issues. Seasonal restrictions primarily involve hurricane season (June-November), which can impact ferry schedules and safety. Visitors must bring all their own provisions, including water, food, and snorkel gear, as there are no facilities, shops, or restaurants on the island, beyond basic composting toilets; respect for the reserve's protected wildlife is paramount.